New Stand-down period for bisphosphonates

POSTED ON  |  12-07-2017

Tildren
The British Horseracing Authority (BHA) would like to advise the Responsible Person (i.e. trainers, owners, breeders) and their veterinary surgeons of a new Rule requiring a mandatory 30 day Stand-Down period from racing following the administration of any bisphosphonate licensed for equine use. This Rule will be effective from 10 August 2017.

The Rule, an addition to Schedule (B)3 – Requirements for horse to run, will read as follows:
“11B The horse must not have been administered
11.B.1any bisphosphonate under the age of three years and six months as determined by its recorded date of birth, or
11.B.2 any bisphosphonate on the day of the race or on any of the 30 days before the day of the race in which the horse is declared to run”

The BHA expectations with regard to the use of bisphosphonates in horses racing or intending to race in Great Britain in order to comply with the Rules of Racing
  • The product used should be licensed for use in horses the UK;
  • The horse must be over three years and six months of age at the time of administration as determined by its recorded date of birth;
  • There must be a diagnosis determined by a veterinary surgeon that supports the use of a bisphosphonate as an appropriate treatment; and
  • The bisphosphonate must be administered by a veterinary surgeon. 
Due to their complex nature and action, the excretion of bisphosphonates may be unpredictable, leading to considerable variation in excretion times. This variability may be increased when bisphosphonates are administered to horses with on-going musculoskeletal disease process, including the possibility that bisphosphonates may be released from bone at a period remote from initial administration. As such, it cannot be guaranteed that future musculoskeletal disease processes will not result in an Adverse Analytical Finding.

As a guide, the BHA are aware of data from studies in normal horses which indicate that if a single dose of Tildren® (CEVA) at 1 mg/kg were administered intravenously, the Detection Time would be unlikely to exceed the Stand-Down period. A discussion between the Responsible Person and their veterinary surgeon is essential when considering administration of any medication which is a Prohibited Substance on raceday. 03 July 2017

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